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Proteins that Controls Sex-linked Disparities in Cancers Found

Nowadays, a cancer diagnosis notice is more like a “death notice” for many families. Did you know that there is a difference between men and women in the incidence and mortality of various cancers? In general, men have about 20% higher cancer incidence and 40% higher mortality than women. The study also found that women had more side effects from chemotherapy and were more likely to develop thyroid cancer. Tracing back to the source, genetic and molecular factors are thought to be responsible for these differences, but the specific mechanisms involved are poorly understood.

A study by the Institute for Biomedical Research (IRB Barcelona) in Barcelona, Spain, recently found that the “behind-the-scenes players” responsible for the tumor differences between the sexes. The results were published in the journal Science Advances.

“We have identified the likely manipulators responsible for the tumor differences between male and female flies,” said Cayetano González, head of the laboratory at the IRB Cell Division in Barcelona.

In this work, researchers analyzed brain tumor development in the vinegar fly Drosophila melanogaster. Drosophila melanogaster has been used in scientific research as a model organism for more than a hundred years, and through them, researchers have discovered many proteins that are closely related to human cancer. In recent decades, various experimental models of human cancer, such as leukemia, neuroblastoma, glioblastoma, and ovarian cancer, have been developed in this animal model.

Specifically, the researchers observed that male flies had more aggressive brain tumors and were more likely to develop malignant tumors than females. They also found that protein expression levels were significantly elevated in brain tumor cells of male flies compared to female flies. Notably, these proteins are also present in humans.

Among these discovered proteins, the researchers focused on Phf7, which is also present in humans. However, in Drosophila, PHF7 is only present in male Drosophila tumor cells and shows strong invasiveness. When the researchers removed this protein from male flies, the tumors were significantly less invasive and returned to levels similar to female flies.

“Our results suggest that proteins responsible for the differences between male and female tumors can be regulated to reduce the malignancy associated with the sex of the affected individuals,” explains Kerry Cristina Molnar, a post-doctoral researcher at the IRB in Barcelona, who led the study.

González added: “Understanding the molecular basis of sex-related differences in cancer incidence and development allows us to find specific treatments for men and women.”

How to Choose the Right Home Health Care Service Provider for You?

A home health care center or service provider offers daily assistance to the patient just to ensure the daily living activities. Home health care services assists people in need to live independently and recover faster from chronic health issue or medical set-backs.

Be it any age, a person recovering post-surgery, or in need of additional support to avoid unnecessary hospitalization can avail the facility of Home Healthcare centers.

Types of Services:

Health Care Services are available to individuals who require immediate skilled nursing care. The services available under the designated term “HOME CARE” includes nursing care, Post-Operative Care, Physiotherapy and many more. With our article we would like to give you a gist on the home health care center that provides 24 hour, 7 days home healthcare services to the patients in need.

Nursing Care:

The highly qualified nurses administer medication, injections and provide medical treatment related to health conditions. With a strict focus on individual needs and care for each and every patient, Porvoo’s caregivers pass through stringent hiring assessments.

Nurses give timely updates to Doctors
Caregivers are punctual with medicines and injections as prescribed
Maintain proper hygiene around the patient
Available at the disposal of the patient and cater to their needs
Post-Operative Care:

To avoid hospitalization which can sometimes be a pressure over finances, Home Health Care Centers like Porvoo Home healthcare make sure that an experienced caregiver is present around the patient as per convenience. Depending on the patient’s health, the medication would vary and will be monitored accordingly.

Critical Care:

Nurses make it their top most priority to take care of the patients who have been recently discharged from the hospital but still need the same amount of care with a home like feeling. Since the procedure is run by the format of International standards, Home Health Care Center has professional nurses and doctors on call for the patient satisfaction.

Specially trained nurses to monitor patients
Complex life support
Intrinsic decision making
Pro-active rather than reactive care
Physiotherapy:

The role of a physiotherapist is to enhance performance of the patient after they have suffered from an injury. Physiotherapy keeps the patient’s muscles and bones inclined with the body and strengthens it.

Muscle Mobilization
Strengthen the joints for better movements
Reduce pain and stiffness
Recover from bone or muscle injury quicker
Sleep Study:

Home Health Care Services Center like Porvoo provide the new state-of-the-art sleep study unit which helps the patient gather more conclusive evidence to overcome sleeping disorders.

Sleep disorders such as sleep apnea, periodic limb movement disorder, narcolepsy, restless legs syndrome, insomnia, and nighttime behaviors like sleepwalking and REM sleep behavior disorder are monitored and diagnosed by the doctor.

To get a better understanding of the disorder or what is happening inside the brain and body of the patient, the tests are run during the patient is asleep.

EEG and ECG:

To measure the electrical activity of the brain, doctors will provide with the best services of EEG (Electroencephalogram). On the other hand, ECG (electrocardiogram) is used for measuring activities of heart.

The well-trained nurses and certified doctors evaluate and detect the tests of the patient to avoid any complications.

Conclusion

Choosing the right home health care can be a task and stressful too yet it can be easy with the right information. There are many questions that arise in the mind of a person while looking for the best home healthcare center. Like how long has it been to this home care, is it genuine or just to earn money, will they offer the treatment as per the requirement of you or your loved one, is the patient confidentiality maintained etc. It becomes really crucial for a person to know the background of the nurse before letting them in their home to follow the procedure. However, that is not the concern at the centers as the background of the caregivers is kept in check by the healthcare center authorities before hiring. Healthcare centers like Porvoo chart a stringent hiring standard and thorough references check.

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Easy Ways to Add Lean Muscle Mass

There is so much advice available today on how to lose weight, from low calorie diets to juice fasting. This information can be confusing for anyone desiring to lose weight over the long term. One beneficial way to lose weight is to add muscle lean muscle mass. Because muscle mass weighs more than fat, there may be no changes on the scales, but the difference will be visible in how your clothes fit.

Adding lean muscle results in a higher resting metabolic rate, a lower fat percentage and a toned physique. However, people with a very high metabolism and lean physique may struggle to add lean muscle mass.

This is where whey protein shakes and bars can help. In order to gain muscle, rather than fat, it is important to consume high protein foods. Whey protein supplements are easily digestible, filling and support any weight-training programme. To learn more about the product in question, why not read whey protein reviews to discover which will be the best product to help you achieve your goals. Building lean muscle mass is not an overnight process; it requires determination, patience and focus.

Good Protein Sources

Weight training is an effective way to add lean muscle mass, but it is important that the body receives enough fuel before, during and after a workout. Good protein sources include nuts, lentils, pulses, cheese, yoghurt, chicken, fish, steak, milk and eggs.

When the microscopic tears occur in muscle tissue, it is important to fuel the body with easily digestible whey protein shakes or bars. Remember to work out the whole body, rather than just focus on the abdominals, back, arms and chest. The largest muscles in the body are the legs, so use squats to build lean muscle mass.

Eat more calories than the body burns off, and on the days when you eat more calories, perform weight training to encourage the growth of lean muscle tissue. Whey protein bars are an effective energy source to consume before a workout and a protein shake can be drank afterward to help the muscles heal and repair.

Rest Equals Gain

Weight training is incredibly taxing on the body. If the body has not received sufficient protein, you may be prone to fatigue. Remember to drink lots of fluid and drink whey protein shakes before and after a workout. Take a rest from exercise every two days, and aim for a maximum four workouts per week.

There are many supplements that can encourage weight gain, but the best whey protein for building muscle will contain a blend of essential amino acids, which is what the body requires to heal and repair the microscopic tears that occur in muscle tissue after lifting weights.

Drink whey protein shakes regularly on the days that you weight train to encourage the growth and repair of lean muscle tissue.

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